Cancer Systems Biology

Cancer Systems Biology
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Research. Miroslava. Cuperlovic-Culf. CONTENTS 9.1 Introduction 143 9.2 Metabolic Changes in Cancer 146 9.3 Metabolic Pathway Modeling and Network Development 150 9.4 Metabolic Profiles of Cancer 154 9.5 Conclusion 159 References 160 9.1 INTRODUCTION Several hypotheses are being explored in an effort to understand the causes of malignant transformation. Currently, a principal view is that the formation of a cancer cell requires a series of mutations in the nuclear ...

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